Yes. You can move an existing Windows installation to a different internal drive without reinstalling every application, provided the source is readable and the destination has enough space.
System clone focuses on the Windows partitions needed to start the OS. A whole-disk clone also copies unrelated data partitions. If the old disk holds a large D: volume you do not want to move, system clone may be more suitable. If you need the entire disk layout, choose disk clone instead.
A normal file copy of C: will not recreate an independent Windows boot installation. Preserve an external backup before either migration operation.
Shut down, select the new drive or its Windows Boot Manager entry in firmware, and temporarily disconnect the old boot disk if feasible. Confirm that Windows actually boots from the new drive in Disk Management. Check files, apps, drivers, and activation before formatting or reusing the source.
Use System clone for a Windows-only migration to another drive. The target drive's contents may be overwritten.
Step 1. Connect the destination drive to the working PC. Open Qiling Disk Master and choose System clone under Tools and utilities.

Step 2. Confirm that the current Windows system disk and its boot partitions are selected as the source. Click Next.

Step 3. Identify the new internal HDD or SSD by capacity and model, select it, and click Next. Move any needed files off it first.

Step 4. Review the system-to-destination layout. If the destination is an SSD, enable Optimize for SSD; then click Proceed.

Step 5. Read the data-loss warning for the destination and confirm only after checking the drive again. Wait for completion. Boot from the destination and verify Windows before disconnecting or erasing the source.

Can I move Windows to a smaller drive? Only if the system partitions and used data fit and the software permits the required resize.
Will the new drive letter be C:? When booted as the active Windows installation, the migrated system normally presents its own system volume as C:.
Choose a system clone for Windows-only migration, inspect the target and preview carefully, then test booting from the new drive before changing the old one.