A USB NVMe enclosure turns an internal M.2 drive into an external USB drive. That is the standard way to clone a laptop or handheld with only one M.2 slot, because the target cannot sit inside the machine during the copy.
This guide covers choosing the enclosure, running the clone from Windows, and the removal steps that prevent a corrupted copy.
The enclosure is only a bridge. The clone speed is limited by the slowest link in the chain, so a fast SSD in a slow enclosure still copies at the enclosure speed.

If the enclosure drive is not visible, check Disk Management first. An uninitialized disk does not appear in File Explorer, but it can still be selected as a clone destination.

A clone that stops near the end is often a USB dropout, not a bad SSD. Move the enclosure to another port, use the cable that came with it, and retry before you replace the drive.
Qiling Disk Master detects the enclosure drive as a normal disk, so you can clone the internal drive and resize the target in one pass.
Watch the video tutorial below to clone the drive step by step with Qiling Disk Master.
Step 1. Open Qiling Disk Master, choose Clone, and then select Disk Clone.

Step 2. Select the source disk and click Next.

Step 3. Select the destination SSD and confirm that its data will be replaced.

Step 4. Choose the clone mode and adjust the partition size for the new drive.

Step 5. Click Proceed, wait for the copy to finish, then eject the enclosure before you unplug it.

If the machine does not see the new drive internally, reseat it and check the M.2 slot. A drive that worked in the enclosure can still fail to seat properly in the slot.
No. NVMe and SATA M.2 drives use different protocols and need different enclosures.
A 10 Gbps enclosure usually settles near 1 GB/s, so a full 1 TB disk takes roughly 20 to 30 minutes.
It is possible over USB4 or Thunderbolt, but boot support varies by firmware and is not reliable.
Usually a weak port, a charge-only cable, or thermal throttling. Try a rear port and the cable supplied with the enclosure.
No. Initializing it as GPT is enough, and the clone will overwrite the layout anyway.
USB copies can drop offline, and a dropped copy can leave the target half-written. Save a system image first so you can restart from a known state.
Watch the video tutorial below to back up Windows and restore it if the clone fails.
Step 1. Open Qiling Disk Master and select System Backup to include the boot partitions.

Step 2. Save the image to a drive other than the target disk and start the backup.

Step 3. Click Proceed to start the system backup and wait patiently until it finishes. You can also tick Shut down the computer when the operation is completed to power off automatically.

Step 4. If the enclosure copy fails, restore the image to the original drive and retry with another USB port.

An NVMe enclosure is the practical answer for single-slot machines, but the USB link sets the speed and the failure modes. Use a matched enclosure, a stable port, and safe ejection before you swap the drive.
For related single-slot guides, see Clone an M.2 SSD with One Slot, Clone an NVMe SSD to a Larger NVMe, Clone a SATA SSD to an NVMe SSD, and Cloned Drive Won't Boot? Fix It.