Blender is one of the most disk-heavy creative applications on Windows. It reads large .blend files on every save and undo, writes cache files for simulations and renders, and keeps a viewport preview cache that grows over a session.
This guide explains what Blender stores, how each cache behaves, and what is worth accelerating with a disk cache.
Blender produces several different kinds of disk files, and each has a different access pattern:
.bphys and .vdb files that are read back on every playback - the pattern described in caching for 3D rendering.The access pattern is a mix of large sequential files and small scattered reads, which is what makes it interesting:
The two layers stack well because Blender's reads are exactly what a disk cache is good at:
A few setups work against each other, and they are easy to avoid:
Blender is one of the best candidates for a disk cache. Undo and simulation playback are the wins; render output is not.
The cleanest setup is to point a disk cache at the volume that holds your .blend files and simulation caches, and let the RAM tier hold the scene file and viewport preview. Qiling Fast Cache uses a RAM tier for the hottest blocks and an SSD tier for the rest, and shows the hit rate in the task list.
Step 1. Install Qiling Fast Cache and open the task list. Open your largest .blend file once before configuring anything.

Step 2. Click the "+" button and select the volume that holds your .blend files and simulation caches, not the render output folder.
Step 3. Size the SSD tier for your largest scene file plus its simulation caches, which is usually a few gigabytes.

Step 4. Work in Blender for an hour, including undo and timeline scrubbing, then read the hit rate - see how to check cache hit rate - and confirm that scene reads are being served from the RAM tier.

No. Rendering is bounded by the GPU or CPU, not the disk. The cache helps undo and playback, not the render itself.
Only if it is large enough. Render intermediates can be several gigabytes, and a small RAM disk will overflow.
The scene file is being read from disk. A disk cache serves it from the RAM tier on the second undo and afterwards.
No. Render frames are written once and never read by the renderer, so caching them wastes space.
Yes, significantly. The same cache files are read on every timeline scrub, which is exactly what the RAM tier is for.
Reconfiguring storage and cache settings is easier to undo when you have a recent image. Qiling Disk Master creates a full Windows backup you can restore from.
Step 1. Install and open Qiling Disk Master. On the home screen, open "Backup and Recovery" and choose "System Backup". This option automatically includes Windows and the hidden boot partitions, so you do not have to select them one by one.

Step 2. Check the source. The disk where Windows is installed and its system partitions are already ticked for you. If you only need your personal documents, run a separate "File Backup" task instead.

Step 3. Click the destination box and choose where the image should be saved. Use an external HDD or SSD, a NAS, or any drive other than the one Windows is installed on, and make sure it has enough free space.

Step 4. Review the task summary and click "Proceed". Wait until the progress bar reaches 100%. Do not unplug the drive or turn off the PC while the backup is running.

Step 1. Open Qiling Disk Master again, go to "Backup and Recovery", and select the recovery option. Your backup images are listed, so pick the one you created before the changes began.

Step 2. Choose the target disk or partition. Normally you restore to the original system disk. If the drive was replaced, select the new disk instead, and the restore rebuilds Windows together with its boot partitions.

Step 3. Preview the restore plan, click "Proceed", and confirm the warning. The PC restarts to finish the job, and Windows comes back exactly as it was on the day the image was created.

Blender is one of the best candidates for a disk cache. Undo reads the same scene file repeatedly, simulation playback reads the same cache files on every timeline scrub, and the viewport preview is small enough to sit in the RAM tier permanently. The cache cannot make rendering faster because that is bounded by the GPU, and it cannot help render output because frames are written once. Point the cache at the volume that holds your .blend files and simulation caches, size the SSD tier for the scene plus its bakes, and read the hit rate after an hour of real work rather than assuming the render folder needs special treatment.
Protect your PC with Qiling Backup—create a system image before your next round of settings changes.
For more creative and caching guides, see caching for 3D rendering, caching for CAD software, RAM disk for video editing, RAM disk for Photoshop scratch disk, and caching for music production.